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Date: Fri, 22 Feb 2019 06:33:38 GMT
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Title: Department of Biochemistry, University of Oxford
Description: Highlighting biochemistry research at Oxford University
Keywords: Biochemistry, Oxford University, Oxford
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Texto: Department of Biochemistry, University of Oxford Department of Biochemistry University of Oxford South Parks Road Oxford OX1 3QU Tel: +44 (0)1865 613200 Fax: +44 (0)1865 613201 Collage of Drosophila third instar larva optic lobeLu Yang, Davis lab First year Biochemistry students at a practical class Image showing the global movement of lipids in a model planar membraneMatthieu Chavent, Sansom lab Anaphase bridges in fission yeast cellsWhitby lab Lactose permease represented using bending cylinders in Bendix software Caroline Dahl, Sansom lab Epithelial cells in C. elegans showing a seam cell that failed to undergo cytokinesis Serena Ding, Woollard lab Bootstrap Slider Home For Undergraduate Applicants For Graduate Applicants Research About the Department Contact For Staff and Current Students News New paper shows how transcription terminates with the help of a phosphatase New research from Lidia Vasilieva's lab sheds light on how transcription termination in eukaryotes is controlled. The findings are published in Cell Reports and demonstrate that conserved mechanisms are used at different steps of transcription Published: 7th November 2018 iGem Gold Medal Award The 2018 Undergraduate Oxford iGEM team have just returned from Boston with a Gold medal and the award for Best Therapeutics Project along with three other award nominations. The iGEM competition gives interdisciplinary teams of students the opportunity to push the boundaries of synthetic biology whilst tackling everyday issues facing the world Published: 7 November 2018 Biochemistry Department at 'IF', the 2018 Oxford Science Festival, 12-14th October 2018 For the first time this year the annual Oxford Science Festival was held in October rather than June, and the Biochemistry Department fronted two stalls in the Town Hall on the weekend 13th and 14thOctober and one in the Weston Library on the afternoon of Friday 12th October Published: 1 November 2018 "The Bacterial World" at the Oxford Natural History Museum An exhibition "The Bacterial World" opens at the Oxford Natural History Museum this Friday and runs until May. It is curated by Judy Armitage with lots of input from Kevin Foster and lots of other bacteriologists around the University. Published: 16 October 2018 All News Items Vacancies There are four job vacancies available Share This Tweet Francis Barr announced as our newHead of Department Francis Barr has been announced as the new Head of the Biochemistry Department with effect from 1st January 2019. He will take over from Professor Mark Sansom after just under 8 highly successful years in charge. Francis joined the Biochemistry Department in 2011 as the EP Abraham Professor of Mechanistic Cell Biology. His research addresses the mechanism by which human cells regulate cell division and membrane traffic and how dysregulation of these pathways can lead to cancer and other human diseases. Read More News Highlight A record-breaking beta barrel allows protein transport across the bacterial outer membrane New research from the Berks (Biochemistry) and Lea (Pathology) groups reveals how proteins are transported across the outer membrane of bacteria responsible for severe dental disease (peridontitis). This work, which is published in Nature [1,2], has uncovered an enormous transmembrane beta barrel structure through which the proteins move. Movies. Electron microscopy density of the PorV (left) and Plug (right) Type 9 protein translocon complexes. The SprA protein is Rainbows coloured, partner proteins are grey. Specular density shows the position of the detergent micelle surrounding the translocon. The complexes are viewed in the same orientation as the Figure below. Movies courtesy of Susan Lea. Pathogenic bacteria must be able to secrete proteins in order to manipulatetheir host organism. Major oral pathogens in the phylum Bacteroidetes , such as Porphyromonas gingivalis , export these proteins across two cell membranes. Protein transport across the outer membrane in these bacteria utilises the recently discovered Type IX Secretion System (T9SS). All protein transport systems have to provide an aqueous pathway across the otherwise hydrophobic membrane bilayer. However, for the T9SS it was unknown which proteins build this protein conducting pathway, or translocon. A joint effort by Drs. Frédéric Lauber and Justin Deme working in the Berks and Lea groups has now identified the translocon and determined its structure in two mechanistically relevant states. Read more Search   Postgraduate Courses Available Studentships Events There are no forthcoming events. Alumni            Keep in touch with the Department Seminars SBMB Seminar Series Muhd Mohd Kipli, Max Epstein, 'SBMB Seminar' Wednesday 27th Feb, 10:00 Main Seminar Room, New Biochemistry Building Infection and Disease Processes Seminar Series Mateusz Kotowski, Amber Stewart, 'Part II Talks' Wednesday 27th Feb, 10:00 Howard Schneiderman Room (third floor, call 75344 for entry), Rodney Porter Building SBCB Seminar Series 'SBCB part II practice talks' Thursday 28th Feb, 14:00 Main Seminar Room, New Biochemistry Building SBMB Seminar Series Joseph Bluck, Dr Felipe Ossa, 'SBMB Seminar' Wednesday 6th Mar, 10:00 Main Seminar Room, New Biochemistry Building All Seminars © 2019 Department of Biochemistry, University of Oxford    Privacy Page Last Updated: 22/02/2019 by Webmaster Website design: Richard Rowley  


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11 www.bioch.ox.ac.uk/about/newsarchive/new-paper-shows-how-transcription-terminates-with-the-help-of-a-phosphatase
12 www.bioch.ox.ac.uk/about/newsarchive/new-paper-shows-how-transcription-terminates-with-the-help-of-a-phosphatase
13 www.bioch.ox.ac.uk/about/newsarchive/igem-gold-medal-award
14 www.bioch.ox.ac.uk/about/newsarchive/igem-gold-medal-award
15 www.bioch.ox.ac.uk/about/newsarchive/biochemistry-department-at-if
16 www.bioch.ox.ac.uk/about/newsarchive/biochemistry-department-at-if
17 www.bioch.ox.ac.uk/about/newsarchive/the-bacterial-world-at-the-oxford-natural-history-museum
18 www.bioch.ox.ac.uk/about/newsarchive/the-bacterial-world-at-the-oxford-natural-history-museum
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